Ultrasound Case: Acute Appendicitis

A 12-year-old male presents with right lower quadrant pain and fever.

Case Presentation

History

  • Chief Complaint: Right lower quadrant (RLQ) pain and fever.
  • History of Present Illness:
    • Periumbilical pain migrating to the RLQ over the course of 24 hours.
    • Pain worsens noticeably with body movement and coughing.
    • Low-grade fever (38.1°C).
    • Anorexia (loss of appetite) for the past 12 hours.
    • No history of diarrhea or accompanying urinary symptoms.
  • Past Medical History: No previous abdominal surgeries; no similar painful episodes in the past.
  • Initial Labs: WBC 14.5 × 10³/µL (neutrophil predominance), CRP 32 mg/L.

EMERGENCY FINDING: This pediatric patient has classic clinical signs of appendicitis (migratory pain, fever, anorexia) alongside elevated inflammatory markers. This combination demands an urgent targeted ultrasound evaluation.


Ultrasound Findings of Appendicitis

  • Non-compressible Appendix: Visualized blind-ended tubular structure measuring greater than 6mm in diameter that fails to collapse under transducer pressure.
  • Wall Thickening: Demonstrates a hyperechoic, edematous wall with a characteristic “target sign” cross-section.
  • Periappendiceal Fat Changes: Prominent hyperechoic (bright) mesenteric fat surrounding the inflamed appendix.
  • Free Fluid: A small volume of complex fluid visualized immediately adjacent to the appendix.
Non-compressible appendix in acute appendicitis
1. Non-compressible appendix: Dilated appendix measuring 8.7mm that completely fails to compress with localized transducer pressure, accompanied by a progressive loss of the normal distinct wall layers.
Target sign in appendicitis ultrasound
2. Target sign appearance: Concentric rings of alternating hyper- and hypoechogenicity seen in short-axis, indicating marked appendiceal wall edema and acute tissue inflammation.
Periappendiceal fat inflammation in appendicitis
3. Inflamed periappendiceal fat: Highly echogenic, bright mesenteric fat surrounding the inflamed appendix (marked by asterisk), accompanied by a trace amount of adjacent free pelvic fluid.

Final Diagnosis: Acute Appendicitis
Confirmed key diagnostic features based on the direct correlation of clinical presentation, elevated systemic inflammatory markers, and classical gray-scale ultrasound findings (aperistaltic, non-compressible dilated appendix with surrounding inflammatory fat tracking).


Differential Diagnosis for Right Lower Quadrant Pain

  • Mesenteric Adenitis: Characterized by multiple enlarged, hypervascular mesenteric lymph nodes in the RLQ, but demonstrates a completely normal, compressible appendix.
  • Omental Infarction: Ultrasound reveals a fixed, focal mass of hyperechoic omental fat that is acutely tender under the probe, with no structural connection to a normal appendix.
  • Right Ovarian Pathology (in females): Conditions like ovarian cysts, hemorrhagic cysts, or ovarian torsion present with acute adnexal pain, but present with normal appendiceal structures.
  • Diverticulitis (typically in adults): Demonstrates localized colonic wall thickening and outpouchings, leaving the appendix unaffected.
  • Gastroenteritis: Presents with diffuse bowel wall thickening and hyperperistalsis (increased bowel activity) often accompanied by clinical diarrhea, with a normal appendix.